MaryRuth’s Liquid Ionic Zinc is a liquid dietary supplement that provides zinc in ionic form, meaning that zinc is found as ions in the solution. While science may not yet completely understand the absorption pathway of zinc in humans, intestinal zinc absorption is mainly mediated by the ZIP4 transporter to import ionic zinc into intestinal cells called enterocytes. It’s been found that when administering zinc orally, the absorption rate is higher when delivered in an aqueous zinc solution (such as the form that our zinc is in) versus receiving the same amount of zinc in a meal.1 


Zinc sulfate is considered GRAS by the FDA, and it was chosen for our product because it has a high reported absorption rate at 71% (compared, for example, to zinc citrate at 61.3%, zinc gluconate at 60.9% or zinc oxide at 49.9%).2 


Please do not hesitate to let me know of any additional questions or if you need further assistance.


1. A Guide to Human Zinc Absorption: General Overview and Recent Advances of In Vitro Intestinal Models 

2. Zinc Absorption by Young Adults from Supplemental Zinc Citrate Is Comparable with That from Zinc Gluconate and Higher than from Zinc Oxide